Research on Micro dosing with sacred plant medicine:

Micro Dosing in general is a fairly young development in the world of plant medicine and psychedelics.   Any actual scientific research is hard to find and at best in the process of being researched.

After working with Grandmother for over 20 years in a ceremonial (macro) setting, our discoveries with micro dosing have been overwhelmingly positive and continue to amaze us.
The vast majority of participants in 2020 and 2021 experienced and increase in:

  • A feeling of well being and being at ease
  • Less stress or an increase of one’s ability to handle stress
  • Increase of joy and appreciation of life
  • Increased sense of connection with the divine
  • Increased sense of connection with self and others.
  • Increase of clarity and presence
  • Healing of specific physical issues
  • Healing of emotional wounds and trauma
  • Healing depression, anxiety, PTSD, ADD and insomnia

Many of our participants received guidance on life questions they were working on at the time during and or after the process.

There are some website that offer some research on the matter, please see a list below:


Given that researchers are only just beginning to scratch the surface of the science of microdosingin general—even with LSD and psilocybin mushrooms—we’ll likely have to wait a while for ayahuasca-specific microdosing studies. There’s also very little research around the therapeutic effects of ayahuasca in general, but clinic trials and anecdotal reports alike suggest that ayahuasca holds promise to treat disorders such as addiction, several mental illnesses, and immune disorders.[11] It’s also been shown to stimulate the growth of new brain cells.

With appropriate supportive settings that include talk therapy and social network support, regular and long-term use of ayahuasca may be the catalyst for lasting lifestyle changes. This is most notable with respect to substance abuse and addiction. One study of an ayahuasca ceremony in Canada, for example, found significant effects on the treatment of addictive behaviors.[12] In a qualitative study surveying a group of people who joined the ayahuasca church UDV (an organization that regularly uses the brew in their religious ceremonies), a large number of the members had histories of alcoholism, substance abuse, domestic violence, and other problem behaviors and lifestyles. These dysfunctional behaviors were virtually resolved after joining the UDV and attending regular ceremonies.

A government-approved addiction treatment center in Peru has integrated ayahuasca into its methodology and has shown significant results among hundreds of patients. Recent animal studies have also shown that ayahuasca-assisted psychotherapy can help eradicate substance abuse disorders.

Ayahuasca may also help ameliorate serotonin deficiencies, which have been related to a host of different disorders, including alcoholism, depression, autism, schizophrenia, attention deficit hyperactivity disorder, and senile dementia. Some small studies suggest that long-term ayahuasca use can possibly increase serotonin availability in the body.[11]

Listen to our podcast episode with Rachel Harris talking about: Overcoming Trauma With Ayahuasca or Click here to read the transcript

The first study to analyze the antidepressant properties of ayahuasca in a controlled setting also showed promising results.[13] Twenty-nine patients with severe depression were given either one session of ayahuasca or a placebo, then analyzed for changes in their depression scores. One day immediately following the sessions, the ayahuasca group scored significantly lower on depression tests compared to the placebo group. After seven days, the placebo group had returned to a normal depression level, while the ayahuasca group still reported a much lower depression score.

Though more research is needed to understand the efficacy of ayahuasca to treat PTSD, anecdotal evidence suggests it could be beneficial. For example, the recent documentary From Shock To Awe follows two war veterans suffering from PTSD as they abandon pharmaceuticals and seek healing through ayahuasca. By the film’s end, the two men have seen their traumas melt away.

It’s important to remember that if ayahuasca does have therapeutic value (which it almost certainly does), gleaning the most healing benefit possible requires the use of ayahuasca in a safe, therapeutic, and supportive environment.